Compared with placebo, the new-generation antidepressants do not produce clinically significant improvements in depression in patients who initially have moderate or even very severe depression. That’s according to a new meta-analysis of clinical trials research. A triumph for the placebo effect! How does it work?
‘Medications’ at Psychology, Philosophy and Real Life, Page 2
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New concise clinical trials lists and research article abstracts are now available in our medications centre, replacing the comprehensive (but difficult to navigate) set of mental health research abstracts we’ve been accumulating for a few years. If you’re looking for the latest research information on common mental health medications, please check them out and let us know what you think!
A new study shows that the results of around a third of drug trials have not been released. Once these are taken into account, the advantage of antidepressants over placebos shrinks significantly. This amounts to seriously misleading the public about the drugs’ effectiveness.
Shire admits there’s a problem with the Daytrana ADHD patch, and fixes it. Following strong feedback from our readers and other users of the Daytrana patch, the company has announced a ‘voluntary market withdrawal’ of faulty Daytrana patches. The company says it is now using an ‘enhanced process’ to ensure the backing of the patch can be easily removed.
If you’ve been following our articles on reader reports about the Daytrana ADHD patch, you’ll know that reader experiences vary widely. With over 170 comments about the methylphenidate transdermal patch, it’s time for another follow-up — and some additional resources for those experiencing problems with the patch.
Evidence that potential blockbuster weight loss drug Acomplia (rimonabant) causes neurological and psychiatric problems and increases the risk of suicide has led to a unanimous vote against the drug by a US FDA advisory panel. Although rimonabant is already being marketed in 37 countries, it is now unlikely the FDA will approve the weight loss drug, to have been sold in the United States under the name ‘Zimulti’, without more positive data on safety.
If you’ve searched our database of clinical trials research exploring drug safety and efficacy, you’ll know the search facility can quickly zero in on relevant drug research. But what if you’d just like to browse through trials by condition or by sponsor, or just find out about trials with a particular status?